Blood urea nitrogen-to-serum albumin ratio and A-DROP are useful in assessing the severity of Pneumocystis pneumonia in patients without human immunodeficiency virus infection

Abstract Introduction There is an increasing incidence of Pneumocystis pneumonia (PcP) among individuals without human immunodeficiency virus (HIV) infection (non-HIV PcP). However, prognostic factors for patients with non-HIV PcP have not been identified. Moreover, A-DROP (for classifying the severity community-acquired pneumonia) or blood urea nitrogen-to-serum albumin ratio (BUN/Alb), which reported to be a predictor mortality pneumonia, has established as efficient factor in PcP. In this study, we analyzed and evaluated ability BUN/Alb ratio. Methods This retrospective study involved chart review medical records 102 diagnosed between January 2003 May 2019 at five facilities. Results Overall, were study. The 30-day rate was 20.5% population. Compared survivors, non-survivors had significantly lower serum levels higher age, corticosteroid dosage at onset, alveolar–arterial oxygen gradient, score, lactate dehydrogenase levels, nitrogen Multivariate analysis showed that high treatment initiation associated risk. receiver operating characteristic curves score highest estimating mortality. Conclusions PcP, independent risk, useful severity.